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. 2015 Apr 6;125(5):1955–1967. doi: 10.1172/JCI78863

Figure 2. The genetic interaction between Sec63 and Xbp1 in polycystic kidney disease is dependent on Pkd1.

Figure 2

(A and B) Hematoxylin and eosin staining of kidney sections with the indicated genotypes at P21. (C) Aggregate data from mice with the indicated genotypes at P21 for kidney weight/body weight ratio, cystic index, and serum BUN levels. Each bar represents individual strains as color-coded in A. n (from left to right) = 5, 5, 7, 5, 4; results are shown as mean ± SEM (ANOVA); ***P < 0.001; **P < 0.01. Scale bars: 2 mm (A), 500 μm (B).