TABLE 2.

Quantitation of nLDL and AgLDL binding to LRP1 cluster II peptides by receptor-ligand binding fluorometric assay

Peptides P1–P3 correspond to the Cys¹⁰⁵¹–Glu¹⁰⁶⁶, Asp¹⁰⁹⁰–Cys¹¹⁰⁴, and Gly¹¹²⁷–Cys¹¹⁴⁰ sequences of human LRP1. Results are shown as mean ± S.D. of six independent experiments performed in duplicate.

	BSA	P1	P2	P3
nLDL	7.76 ± 0.32	7.16 ± 0.42	7.53 ± 0.62	7.03 ± 0.36
AgLDL	16.19 ± 1.72	17.15 ± 2.08	16.49 ± 2.63	50.55 ± 3.13a

^a p < 0.05 versus BSA-bound cholesterol (see “Results” for details).