Table 3.
Characteristic | Ovarian and Fallopian Tube Cancers |
Ovarian, Fallopian Tube, and Primary Peritoneal Cancers |
||
---|---|---|---|---|
No. | 95% CI | No. | 95% CI | |
No. of women-years | 296,911 | 296,911 | ||
No. of surgeries | 640 | 640 | ||
Primary ovarian (C56) and tubal (C57.0) malignancies and primary peritoneal cancer (C48.2) within 1 year of screen (includes borderline and ovarian neoplasm of uncertain behavior) | ||||
Screen positive | 154 | 166 | ||
Screen negative | 32 | 35 | ||
Sensitivity | 82.8 | 76.6 to 87.9 | 82.6 | 76.6 to 87.6 |
Specificity | 99.8 | 99.8 to 99.9 | 99.8 | 99.8 to 99.9 |
PPV | 24.1 | 20.8 to 27.6 | 25.9 | 22.6 to 29.5 |
No. of operations per screen positive | 4.2 | 3.9 | ||
Primary invasive epithelial ovarian, tubal, and primary peritoneal malignancies within 1 year of screen (excludes borderline epithelial ovarian neoplasms) | ||||
Screen positive | 133 | 145 | ||
Screen negative | 22 | 25 | ||
Sensitivity | 85.8 | 79.3 to 90.9 | 85.3 | 79.1 to 90.3 |
Specificity | 99.8 | 99.8 to 99.8 | 99.8 | 99.8 to 99.8 |
PPV | 20.8 | 17.7 to 24.1 | 22.7 | 19.5 to 26.1 |
No. of operations per screen positive | 4.8 | 4.4 |
NOTE. All codes are International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10).
Abbreviations: MMS, multimodal strategy; PPV, positive predictive value.