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. 2015 May 13;115(11):5413–5461. doi: 10.1021/acs.chemrev.5b00003

Figure 26.

Figure 26

Homodimeric PRMT1 contains two active sites and a central hole (PDB code 1OR8). Monomeric PRMT7 from Mus musculus harbors only one active site and does not possess a central hole (PDB code 4C4A). Homodimeric PRMT7 from T. brucei contains two active sites and does not possess a central hole (PDB code 4M37).