Table 1.

miRNAs in the pathogenesis of systemic lupus erythematosus (SLE).

miRNA	Target	Regulated Process	References
let-7a	IL6	IL6 induction	[65]
let-7c	Blimp1, SOCS1	Activation of DCs	[64]
miR-125a	KLF13	CCL5 induction in T-cells	[81]
miR-126	DNMT1	DNA methylation in T-cells	[73]
miR-146a	TRAF6, IRAK1	NFκB mediated inflammatory response	[53]
	TRAF6, IRAK1, IRAK2	RIG-I-dependent anti-viral pathway	[54]
	IRF5, STAT1	Type I IFN induction and signaling	[55]
miR-148a	DNMT1	DNA methylation in T-cells	[71]
miR-150	SOCS1	Renal fibrosis	[94]
miR-155	MyD88, TAB2	TLR/IL1 inflammatory pathway	[57,58]
	SOCS1	Type I IFN signaling	[59]
	PP2Ac	IL2 induction	[110]
miR-155*	IRAKM	Type I IFN induction	[ 60]
miR-17~92	PTEN, Bim	Proliferation of lymphocytes	[84]
	Rora, PHLPP2	Differentiation and function of Tfh cells	[85,86]
miR-21	RASGRP1	DNA methylation in T-cells	[71]
miR-23b	TAB2, TAB3, IKKα	IL17, TNFα, IL1β signaling	[91]
miR-29b	Sp1	DNA methylation in T-cells	[74]
miR-30a	Lyn	Activation of B-cells	[87]
miR-31	RhoA	IL2 induction in T-cells	[80]
miR-3148	TLR7	TLR7 inflammatory pathway	[63]