Table 2.
Genotype frequencies of PDCD1 SNPs among SLE patients and healthy controls of different ethnics.
| SNP | Genotype Frequency, n | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chinese | Malay | Indian | |||||||
| SLE | Control | p Value | SLE | Control | p Value | SLE | Control | p Value | |
| PD1.1 | |||||||||
| AA | 28 | 28 | ns | 8 | 7 | ns | 1 | 0 | ns |
| AG | 53 | 53 | 27 | 33 | 2 | 0 | |||
| GG | 34 | 34 | 35 | 30 | 12 | 15 | |||
| PD1.3 | |||||||||
| AA | 0 | 0 | ns | 0 | 0 | ns | 0 | 0 | ns |
| AG | 0 | 0 | 1 | 1 | 1 | 1 | |||
| GG | 115 | 115 | 69 | 69 | 14 | 14 | |||
| PD1.5 | |||||||||
| CC | 56 | 46 | ns | 25 | 44 | 0.0022 | 7 | 0 | 0.0063 |
| CT | 49 | 60 | 42 | 21 | 0.0006 | 6 | 15 | 0.0007 | |
| TT | 10 | 9 | 3 | 5 | ns | 2 | 0 | ns | |
| PD1.6 | |||||||||
| AA | 52 | 47 | ns | 18 | 14 | ns | 2 | 0 | ns |
| AG | 49 | 55 | 33 | 35 | 2 | 4 | |||
| GG | 14 | 13 | 19 | 21 | 11 | 11 | |||
ns: Non-significant; p value in bold: significant.