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Reduced in vitro maturation rate of AR−/− oocytes. Histogram shows the in vitro maturation rate of AR+/+ and AR−/− oocytes. After 18 h of in vitro culture, fewer AR−/− oocytes could reach to metaphase II (60%) compared with AR+/+ oocytes (95%) (right panel); In the meantime, about 30% of AR−/− oocytes were remained in germinal vesicle breakdown (GVBD) stage (left panel), n = 100 follicles per genotype.
