Table 4.
Biomarkers with statistically significant diagnostic value for heart failure in univariate analysis.
| Analysis | Variable | Parameter—B | SE | p | OR | 95% CI | c Statistic | |
|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Galectin-3 | −0.039 | 0.027 | 0.145 | 0.961 | 0.912 | 1.014 | 0.549 |
| TNF-α | −0.002 | 0.006 | 0.800 | 0.998 | 0.986 | 1.011 | 0.418 | |
| CT-1 | 0.010 | 0.002 | 0.000 | 1.010 | 1.006 | 1.015 | 0.830 | |
| TGF-β | −0.630 | 0.124 | 0.000 | 0.533 | 0.418 | 0.679 | 0.878 | |
| Syndecan | 0.675 | 0.173 | 0.000 | 1.964 | 1.398 | 2.759 | 0.781 | |
| NT-proBNP | 0.007 | 0.002 | 0.000 | 1.007 | 1.003 | 1.010 | 0.873 | |
| CysC | 2.714 | 0.742 | 0.000 | 15.091 | 3.523 | 64.645 | 0.793 | |
| NGAL | −0.010 | 0.006 | 0.123 | 0.990 | 0.978 | 1.003 | 0.673 | |
| PIIINP | 0.374 | 0.206 | 0.069 | 1.454 | 0.971 | 2.177 | 0.590 | |
| IL1R1 | −1.640 | 0.850 | 0.054 | 0.194 | 0.037 | 1.025 | 0.587 | |
| CRP | 0.153 | 0.093 | 0.099 | 1.165 | 0.972 | 1.398 | 0.504 | |
TNF-α, tumor necrosis factor α; CT-1, cardiotrophin 1; TGF-β, transforming growth factor β; NT-proBNP, N-terminal pro-brain natriuretic peptide; CysC, cystatin C; NGAL, neutrophil gelatinase-associated lipocalin 2; PIIINP, collagen III N-terminal propeptide; IL1R1, interleukin 1 receptor, type I; CRP, C-reactive protein.