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. 2015 May 18;16(5):11385–11397. doi: 10.3390/ijms160511385

Table 3.

Combined effect analysis of two genes (BMPR-IB/BMP-15, BMPR-IB/FSHR and BMP-15/FSHR) on litter size.

Gene Genotype Total Population Small Tail Han Sheep Hu Sheep
No. of Ewes Litter Size No. of Ewes Litter Size No. of Ewes Litter Size
BMPR-IB/BMP-15 ++/++ 29 1.17 ± 0.071 Dd 13 1.15 ± 0.104 Bc 16 1.19 ± 0.101 Bbc
++/G+ 9 1.22 ± 0.147 Dcd 6 1.33 ± 0.211 Bbc 3 1.00 ± 0.000 Bc
B+/++ 1029 1.66 ± 0.020 BCbc 450 1.71 ± 0.033 ABbc 579 1.63 ± 0.025 ABabc
BB/++ 93 1.82 ± 0.073 ABb 55 1.84 ± 0.089 ABab 38 1.79 ± 0.126 ABab
B+/G+ 412 1.93 ± 0.036 ABab 315 1.87 ± 0.041 ABab 106 2.13 ± 0.068 Aa
BB/G+ 49 2.35 ± 0.129 Aa 30 2.47 ± 0.157 Aa 19 2.16 ± 0.220 Aa
BMPR-IB/FSHR ++/TC 23 1.17 ± 0.081 Dd 8 1.13 ± 0.125 Bd 15 1.20 ± 0.107
++/TT 15 1.20 ± 0.107 Dcd 11 1.27 ± 0.141 Bcd 4 1.00 ± 0.000
B+/TT 518 1.67 ± 0.030 BCbcd 431 1.69 ± 0.033 Bbcd 87 1.57 ± 0.069
B+/TC 896 1.76 ± 0.022 BCbcd 315 1.86 ± 0.042 ABbcd 581 1.70 ± 0.026
BB/TT 58 1.91 ± 0.099 BCbc 38 1.89 ± 0.112 ABbcd 20 1.95 ± 0.198
BB/TC 81 2.02 ± 0.093 BCb 45 2.16 ± 0.123 ABabc 36 1.86 ± 0.139
B+/CC 36 2.31 ± 0.125 ABab 19 2.26 ± 0.168 ABab 17 2.35 ± 0.191
BB/CC 3 3.000 ± 0.577 Aa 2 3.00 ± 1.000 Aa 1 3.00
BMP-15/FSHR ++/TT 425 1.63 ± 0.032 Cc 340 1.66 ± 0.036 Bc 85 1.51 ± 0.072 Cd
++/TC 707 1.67 ± 0.024 Cc 169 1.78 ± 0.058 ABbc 538 1.63 ± 0.025 BCcd
G+/TT 166 1.81 ± 0.055 BCc 140 1.78 ± 0.60 ABbc 26 2.00 ± 0.136 ABCbcd
G+/TC 293 2.01 ± 0.045 BCbc 199 1.97 ± 0.055 ABabc 94 2.10 ± 0.080 ABCabc
++/CC 19 2.21 ± 0.181 ABab 9 2.22 ± 0.222 ABab 10 2.20 ± 0.291 ABab
G+/CC 20 2.50 ± 0.170 Aa 12 2.42 ± 0.260 Aa 8 2.63 ± 0.183 Aa

The numbers in the table are the LSMEAN ± standard error of phenotypic value. The different superscript letters in the same column for each gene in lowercase represent significant level at p < 0.05, which letters in uppercase represent significant level at p < 0.01, and the same letter represents no significant difference (p > 0.05).1 B means FecB mutation; G means FecXG mutation; + means wild-type; C means FSHR g.47C>T mutation; T means wild-type.