Table 3.
Genotype frequency of prostate stem cell antigen (PSCA) variation and their association with gastric adenocarcinoma (GAC) risk.
| SNP ID | Genotype | No. (Frequency) | OR | (95% CI) | p | |||
|---|---|---|---|---|---|---|---|---|
| Case (n = 476) | Control (n = 481) | |||||||
| rs2294008 | CC | 227 | (47.8) | 261 | (54.4) | 1.00 | ||
| CT | 207 | (43.6) | 183 | (38.1) | 1.30 | (1.00–1.70) | 0.053 | |
| TT | 41 | (8.6) | 36 | (7.5) | 1.31 | (0.81–2.12) | 0.272 | |
| CT + TT | 248 | (52.2) | 219 | (45.6) | 1.30 | (1.01–1.68) | 0.042 * | |
| rs3736001 | GG | 382 | (80.6) | 402 | (83.6) | 1.00 | ||
| GA | 88 | (18.6) | 74 | (15.4) | 1.25 | (0.89–1.76) | 0.195 | |
| AA | 4 | (0.8) | 5 | (1.0) | 0.84 | (0.22–3.16) | 0.936 | |
| GA + AA | 92 | (19.4) | 79 | (16.4) | 1.23 | (0.88–1.71) | 0.229 | |
| rs2976392 | GG | 190 | (43.6) | 231 | (51.2) | 1.00 | ||
| GA | 208 | (47.7) | 184 | (40.8) | 1.37 | (1.04–1.81) | 0.024 * | |
| AA | 38 | (8.7) | 36 | (8.0) | 1.28 | (0.78–2.10) | 0.322 | |
| GA + AA | 246 | (56.4) | 220 | (48.8) | 1.36 | (1.04–1.77) | 0.023 * | |
| rs10216533 | GG | 237 | (53.6) | 256 | (54.4) | 1.00 | ||
| GA | 152 | (34.4) | 176 | (37.4) | 0.93 | (0.71–1.23) | 0.626 | |
| AA | 53 | (12.0) | 39 | (8.3) | 1.47 | (0.94–2.30) | 0.093 | |
| GA + AA | 205 | (46.4) | 215 | (45.7) | 1.03 | (0.79–1.34) | 0.824 | |
* Statistically significant (p < 0.05).