Table 1.
Study | SNP/Risk Allele | Country | Ethnicity | Case # | Control # | Quality Score | Genotyping Platform |
---|---|---|---|---|---|---|---|
[4] | rs10757278/A | China | Asian | 432 | 430 | 8 | GenomeLab SNPstream |
[9] | rs1333049/C | China | Asian | 425 | 1377 | 8 | TaqMan |
[16] | rs1333049/C | China | Asian | 142 | 192 | 8 | PCR |
[17] | rs1333049/C | China | Asian | 520 | 560 | 8 | NA |
[18] | rs10757278/C | China | Asian | 1515 | 5019 | 8 | NA |
[5] | rs1333049/C | Japan | Asian | 589 | 2475 | 9 | MALDI-TOF MS |
[10] | rs10757278/A | India | Asian | 87 | 150 | 8 | PCR |
[6] | rs1333049/C | Pakistan | Asian | 2587 | 2573 | 8 | NA |
[11] | rs10757278/A | Russia | Siberian | 197 | 417 | 8 | NA |
[12] | rs10757278/G | Italy | Caucasian | 416 | 308 | 8 | ABI PRISM 7900HT |
[7] | rs10757278/G | Germany | Caucasian | 3657 | 1211 | 9 | TaqMan |
[3] | rs10757278/G | Iceland (discovery) | Caucasian | 1067 | 6728 | 9 | IlluminaHap300 |
[3] | rs10757278/G | Iceland (replication) | Caucasian | 665 | 3533 | 9 | IlluminaHap300 |
[3] | rs10757278/G | United States (Atlanta) | Caucasian | 596 | 1284 | 9 | IlluminaHap300 |
[3] | rs10757278/G | United States (Philadelphia) | Caucasian | 582 | 504 | 9 | IlluminaHap300 |
[3] | rs10757278/G | United States (Durham) | Caucasian | 1137 | 718 | 9 | IlluminaHap300 |
[8] | rs10757278/G | United States | Caucasian | 310 | 560 | 9 | TaqMan |
n = 14,924 | n = 28,039 |
The Quality Score of included studies were scored based on the criteria developed by Clark et al. [19] to evaluate the quality of genetic association studies. #, the number of case and control samples; NA, Genotyping platform is not available.