Table 2.
Chronobiological analysis of liver and blood samples
| L-Trp liver | 5-HTP liver | 5-HT liver | Enzymatic activity TPH | MAO-A mRNA | 5-HT serum | 5-HT plasma | Count of platelets | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AL | DRF | AL | DRF | AL | DRF | AL | DRF | AL | DRF | AL | DRF | AL | DRF | AL | DRF | |
| Period | 8 | 24 | 12 | 12 | 24 | 12 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 8 | 24 |
| Amplitude | 0.24 | 0.14 | 0.19 | 0.19 | 0.45 | 0.21 | 12 | 8.87 | 1.35 | 0.65 | 97 | 92 | 6 | 5 | 317 | 197 |
| Mesor | 0.60 | 0.41 | 0.73 | 0.82 | 0.80 | 0.63 | 22 | 17.5 | 4.2 | 1.3 | 19 | 176 | 13 | 13.5 | 1269 | 1404 |
| % rhythm | 47.2 | 55.7 | 21 | 50 | 58 | 35 | 50 | 75 | 43 | 54 | 85 | 75 | 60 | 44 | 66 | 48 |
L-TRP, L-tryptophan; 5-HTP, 5-hydroxytryptophan; 5-HT, serotonin; TPH, tryptophan hydroxylase; MAO-A, monoamine oxidase isoform A; DRF, daytime restricted feeding.