Table 1.
Baseline characteristics of control rats and diabetic rats given as mean ± SE or median (interquartile range).
| Variable | Control | Diabetic | P-value |
|---|---|---|---|
| Number | 14 | 15 | |
| Body weight (g) | 316 ± 8.3 | 286 ± 9.4 | 0.02 |
| Kidney weight (g) | 0.91 ± 0.02 | 1.02 ± 0.01 | 0.001 |
| Blood glucose (mmol) | 5.5 ± 0.5 | 19.9 ± 1.2 | <0.001 |
| MAP (mmHg) | 109 ± 3.5 | 108 ± 4.4 | 0.44, ns |
| Serum creatinine (μmol/L) | 18.3 ± 0.6 | 19.3 ± 0.8 | 0.54, ns |
| LDH (U/L) | 97 (119) | 80 (59) | 0.13, ns |
| Serum albumin (g/L) | 37.4 ± 0.62 | 34.3 ± 0.63 | 0.003 |
| Albuminuria (mg 24 per hour) | 60.8 (76) | 115 (41) | 0.02 |
| U-GGT U/L | 0.9 (0.8) | 48 (140) | <0.001 |
MAP, mean arterial blood pressure; LDH, lactate dehydrogenase; U-GGT, urine gamma-glutamyl transpeptidase.