Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 25;3(5):e12411. doi: 10.14814/phy2.12411

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Long-term plasticity in CD-fed and KD-fed animals. (A) Representative examples of field postsynaptic potentials and superimposed population spikes recorded during quiet waking. Traces from baseline (dashed) and 60 min after (solid) θ-burst stimulation to induce LTP in rats fed the CD or KD. Baseline stimulation was calibrated to produce 50% of maximal population spike amplitude, and, using this same stimulation intensity, robust potentiation was produced by θ-burst stimulation. Traces are averages of five single traces; standard errors are indicated in gray. (B) θ-burst stimulation induced long-term plasticity over 48 h in CD-fed and KD-fed animals. Measurements were taken once every minute 15 min before and after induction (minute 0), and at decreasing frequency as time progressed and up to and including 48 h. There was a significant effect of dietary treatment in the amplitude of potentiation which remained until the last recording timepoint. Diet F_(1,803) = 9.1, P = 0.006; Diet-x-Time F_(35,803) = 6.6, P < 0.001. *P < 0.05, **P < 0.002 CD vs. KD.