Table 4.

Patients treating during pregnancy

Patient 1	Patient 2	Patient 3
Age: 29. Episodic Migraine with Aura.	Age: 30. Chronic Migraine without aura.	Age: 32. Chronic Migraine without aura.
Pre-pregnancy migraine pattern:	Pre-pregnancy migraine pattern:	Pre-pregnancy migraine pattern:
Frequency: 12 days/month. Duration: 0.5–1 day.	Frequency: 10 days/month plus daily background pain.	Frequency: 15 days/month. Duration: 1–2 days.
Treatment: Triptan and sleep.	No effective treatment.	Treatment: frovatriptan, Syndol (paracetamol [acetaminopheno] + codeine + doxylamine + caffeine) and Naproxen, goes to bed.
During pregnancy:	During pregnancy:	During pregnancy:
Frequency: 2–4 days per week, Duration of 2–3 days, severe and in bed. Estimated 90 % reduced ability to function.	16 days: acute attacks plus daily background pain. Duration: 1 day. Estimated 50 % reduced ability to function.	Treatment: Dihydocodeine during the early pregnancy with partial benefit. Estimated 60 % reduced ability to function.
TMS response: 2 consecutive pulses repeated after 15 min. Consistent reduced pain severity and duration. Could return to function and did not need to go to bed.	TMS response: 4 pulses per day (2 consecutive pulses repeated after 15 min). Stopped attack escalation and reduced the severity back down to a mild tolerable level within 1–2 h. Associated symptoms resolved or did not develop.	TMS response: a single pulse repeated after 15–30 min; up to 4 pulses per attack. Initially combined with dihydrocodeine. Subsequently used sTMS only and could abort the attack within an hour. Associated symptoms rarely developed.