Table 1.

Increased cardiac mortality only in old studies

Patient enrolment, years	Increase in risk for cardiac death (hazard ratio) in follow-up
	Up to 10 years	10–14 years	15–19 years	≥ 20 years
1973–1982	1.19	1.35	1.64	1.90
1983–1992	0.99	1.02	1.11	1.21
1993–2002	0.97	0.99		no data
2003–2008	1.00	no data	no data	no data

Irradiated patients had a higher rate of cardiac deaths compared to the control group without irradiation. When listing the studies in chronological order, this was only significant in studies that recruited until 1982 (significant risks are highlighted in the table in italics). In studies with recruitment from 1983 to 1992, a very small, not more significant risk resulted after more than 15 years. In subsequent work, increased cardiac mortality was no longer observed (modified from [2]).