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. 2015 Jun 1;16(Suppl 9):S6. doi: 10.1186/1471-2105-16-S9-S6

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Copyright © 2015 Palma et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Mechanism of action of A-riboswitch Cartoon showing the OFF (left) and ON (right) states of the A-riboswitch. When ligand is not present the ribosome binding site (orange, RBS) is paired with a portion of the aptamer and translation is blocked. When ligand is present the RBS is free to interact with the ribosome and translation can be initiated.