Table 1.
Risk factors of polyomavirus BK infection in kidney transplant patients suspected to have nephropathy
| No | Age (yrs) | Sex | Creatinine (mg/dL) | Cell cept (mg) | Cyclosporine (mg/kg/day) | Tacrolimus (mg/kg/day) | Prednisolone (mg/mL) | Pathology decision | Polyomavirus BK infection in plasma | Polyomavirus BK infection in tissue | Transplant duration (months) | Polyomavirus BK copy number (genome copy/mL) | Cytomegalovirus active infection (PP65 antigenemia) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 22 | Male | 7 | 500 | NFD | 2 | 10 | Acute cellular rejection grade (ΙΙB), acute tubular necrosis | +a | –a | 9 | 26600 | NFDb |
| 2 | 31 | Male | 1.7 | 1500 | NFD | 3 | 5 | C4d+, no rejection | – | + | 11 | 20 | NFD |
| 3 | 44 | Female | 1.8 | 2000 | NFD | 3 | 5 | Acute tubulointrestitial nephritis | + | – | 4 | 20 | NFD |
| 4 | 20 | Female | 2.4 | 2000 | NFD | 2 | 2.5 | Chronic allograft nephropathy (grade Ι) | – | + | 12 | 20 | +c |
| 5 | 15 | Male | 5.2 | 1000 | 100 | NFD | 5 | Acute tubulointrestitial nephritis, chronic allograft nephropathy (grade Ι) | – | + | 26 | 20 | NFD |
| 6 | 33 | Male | 2.8 | 1500 | NFT | 3 | 25 | Acute cellular rejection grade (ΙB) | + | – | 11 | 20 | NFD |
| 7 | 44 | Male | 1.6 | 2000 | 200 | NFD | 7.5 | Acute cellular rejection grade (ΙA), chronic allograft nephropathy (grade Ι) | + | – | 34 | 20 | NFD |
| 8 | 33 | Male | 8.4 | 1000 | NFT | 2 | 20 | Acute cellular rejection (grade ΙΙB) | + | – | 28 | 20 | + |
| 9 | 63 | Female | 2.3 | 2000 | 100 | NFD | 5 | Acute tubulointrestitial nephritis, chronic allograft nephropathy (grade Ι) | – | + | 15 | 40 | NFD |
| 10 | 38 | Female | 2.5 | 1500 | NFD | 3 | 5 | NFD | + | – | 18 | 20 | + |
| 11 | 20 | Female | 3.3 | 1500 | 250 | NFD | 15 | Acute cellular rejection | – | + | 15 | 20 | + |
| 12 | 43 | Female | 6 | 2000 | NFD | 3 | 5 | Acute tubulointrestitial nephritis | – | + | 11 | 20 | + |
| 13 | 42 | Female | 4 | 1000 | NFD | 2 | 5 | Acute cellular rejection (grade ΙA) | + | – | 5 | 120 | NFD |
| 14 | 50 | Female | 2.8 | 1000 | NFD | 1 | 7.5 | Acute cellular rejection | – | + | 3 | 20 | NFD |
| 15 | 27 | Male | 8 | 1000 | NFD | NFD | 5 | Acute tubulointrestitial nephritis, acute cellular rejection (grade Ι), chronic allograft nephropathy (grade Ι) | + | – | 3 | 20 | NFD |
| 16 | 45 | Male | 2.4 | 2000 | NFD | 4 | 5 | Acute cellular rejection | Neg | + | 13 | 20 | NFD |
| 17 | 30 | Female | 2.5 | 2000 | NFD | 3 | 5 | Acute cellular rejection grade (ΙΙA), Ab–medated, C4d+ and no rejection | + | – | 13 | 50 | NFD |
| 18 | 36 | Female | 6.3 | 2000 | NFD | 4 | 5 | Acute cellular rejection, acute tubular necrosis | Neg | + | 9 | 20 | NFD |
| 19 | 54 | Male | 3.5 | 1000 | NFD | 2 | 10 | Acute tubulointrestitial nephritis, acute cellular rejection | + | – | 20 | 20 | NFD |
| 20 | 65 | Male | 3.2 | 1500 | 50 | NFD | 5 | NFD | + | NFT | 36 | 40 | NFD |
| 21 | 26 | Female | 2.8 | 1500 | NFD | 3 | 5 | NFD | + | NFT | 5 | 40 | NFD |
| 22 | 51 | Male | 2.8 | 2000 | 125 | NFD | 5 | NFD | + | NFT | 5 | 20 | – |
| 23 | 34 | Male | 6.4 | 750 | NFD | NFD | 5 | NFD | + | NFT | 60 | 52 | NFD |
| 24 | 36 | Female | 1.7 | 1000 | 225 | NFD | 5 | NFD | + | NFT | 7 | 20 | NFD |
| 25 | 30 | Male | 1.7 | 1500 | NFD | 2 | 5 | NFD | + | NFT | 7 | 2360 | NFD |
| 26 | 31 | Male | 1.8 | 1500 | NFD | 2 | 5 | NFD | + | NFT | 12 | 62 | NFD |
a: +=Positive; –=Negative; b: NFD=Data not found, c: +=Rate antigenemia positivity