Table 1. Differentially expressed proteins in relation to diabetes or liver disease identified by iTRAQ^a in mouse serum after 5 mg/kg/d PFOA exposure for 28 d.

Accession	Gene symbolb	Fold change (P/C)c	Accession	Gene symbolb	Fold change (P/C)c
IPI00135189	Aacs	7.28	IPI00117042	Gfap	3.28
IPI00119114	Acadl	3.00	IPI00129243	Ggh	2.14
IPI00126248	Acly	2.75	IPI00319652	Gpx1	2.07
IPI00662244	Agl	2.39	IPI00469893	Habp2	0.64
IPI00626662	Aldh1a1	3.04	IPI00409148	Hp	5.34
IPI00124372	Aldh9a1	2.06	IPI00330804	Hsp90aa1	2.74
IPI00127206	Aldob	3.24	IPI00128522	Hspb1	3.67
IPI00127352	Ambp	1.62	IPI00312295	Ifnar2	1.52
IPI00128206	Angptl3	1.87	IPI00556721	Igfals	0.53
IPI00331221	Apoa5	0.55	IPI00313327	Igfbp2	1.86
IPI00119676	Apoc1	1.66	IPI00112485	Igfbp3	1.57
IPI00130382	Apom	0.50	IPI00113057	Klkb1	0.57
IPI00117914	Arg1	6.91	IPI00475209	Masp1	1.79
IPI00314788	Asl	1.74	IPI00111793	Nid1	2.08
IPI00130950	Bhmt	2.62	IPI00317356	Pon1	0.21
IPI00113996	Blvrb	1.80	IPI00338018	Postn	0.46
IPI00312058	Cat	4.37	IPI00121788	Prdx1	2.41
IPI00116283	Cct3	1.67	IPI00117910	Prdx2	2.68
IPI00135087	Cops5	1.74	IPI00131406	Psma7	1.91
IPI00111908	Cps1	2.12	IPI00319525	Pygl	1.67
IPI00138274	Cryab	4.18	IPI00225275	Pygm	3.75
IPI00119622	Csad	2.24	IPI00903401	Serpina1c	0.26
IPI00111013	Ctsd	1.75	IPI00118286	Sfn	2.56
IPI00108061	Cxcl12	0.61	IPI00125333	Slpi	0.66
IPI00331394	Dnpep	1.73	IPI00459493	Tcp1	1.52
IPI00307837	Eef1a1	1.53	IPI00127560	Ttr	0.48
IPI00466069	Eef2	1.97	IPI00118344	Ugdh	2.71
IPI00321617	Ephx2	4.82	IPI00131204	Ugp2	3.86
IPI00330843	F12	1.95	IPI00227299	Vim	2.02
IPI00307890	F7	0.52	IPI00129215	Vnn1	4.69
IPI00122312	Fgg	1.56	IPI00129240	Vtn	0.34

^aiTRAQ was performed on four individual samples from each group, respectively.

^bFull names of the proteins are referred to in Table S2.

^ciTRAQ fold changes (P/C) were the average protein fold change of four individual samples. A protein with ≥ 1.5-fold or ≤ 0.66-fold difference and a p-value ≤ 0.05 was regarded as differentially expressed.