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Effects of the various immunosuppressive agents on the expression of HO-1 in HBZY-1 mesangial cells at 24 h (immunocytochemistry; magnification, x80). HO-1 was intensively expressed in the caryon and cytoplasm in MMF, CsA and Tac groups, particularly in the MMF group.(A) negative control; (B) control; (C) CsA group; (D) MMF group; (E) RAPA group; (F) Tac group. HO-1, heme oxygenase-1; RAPA, rapamycin; CsA, cyclosporine A; Tac, tacrolimus; MMF, mycophenolate mofetil.
