Table 2.
A. terreus pellet diameters during lovastatin biosynthesis to be found in literature
| Average pellet diameter (μm) | Lovastatin titre (mg LOV l−1) | Bioreactor*; carbon source; aeration/stirring | Literature |
|---|---|---|---|
| 100–300 | Not given | 500-l STB; not given; controlled pO2 at 50 % | [5] |
| 1,500 and 2,000 | 20 and 40 | 5-l STB; lactose; 800 and 300 rpm | [2] |
| 2,000–3,000 | Not given | 17-l FBB; lactose; vvm = 1 liar l−1 min−1 | [15] |
|
750–1,600 650–1,350 |
331 458 |
125-ml ShF; lactose; shaking speed not given 5-l STB; lactose; vvm = 1 liar l−1 min−1, 225–425 min−1 |
[1] |
| 3,500–5,650 | 900 | 2-l ALB; glucose and milk powder; 1.5 lair l−1 min−1 | [25] |
| 1,000–3,800 | From 30 to 70 | 150-ml ShF; lactose; 110 min−1 | [6] |
| 1,400–6,200 | From 30 to 90 | 150-ml ShF; lactose; 110 min−1 | This work |
STB stirred tank bioreactor, FBB fluidised bed bioreactor, ShF shake flask, ALB air-lift bioreactor