Table I.
Pathways significantly enriched with differentially expressed genes in the NCI-H520/R cells.
| Pathway ID | Definition | Fisher’s P-value |
|---|---|---|
| hsa04621 | NOD-like receptor signaling pathway | 0.0023104 |
| hsa04010 | MAPK signaling pathway | 0.0134484 |
| hsa04662 | B cell receptor signaling pathway | 0.0146623 |
| hsa04630 | JAK-STAT signaling pathway | 0.0175341 |
| hsa04722 | Neurotrophin signaling pathway | 0.0178688 |
| hsa04910 | Insulin signaling pathway | 0.0241512 |
| hsa04340 | Hedgehog signaling pathway | 0.0379188 |
| hsa04012 | ErbB signaling pathway | 0.0493879 |
| hsa04210 | Apoptosis | 0.0493879 |
Significantly enriched pathways (P<0.05) are listed, following manual removal of human disease pathways. NOD, nucleotide-binding oligomerization domain; MAPK, mitogen-activated protein kinas; JAK, Janus kinase; STAT, signal transducers and activators of transcription.