Table I.
Effects of combined ASA and sCT treatment on serum parameters.
| Serum component | Sham | OVX | OVX+ASA | OVX+sCT | OVX+sCT+ASA |
|---|---|---|---|---|---|
| Ca (mmol/l) | 2.67±0.27 | 2.47±0.14 | 2.55±0.22 | 2.52±0.20 | 2.45±0.25 |
| Pi (mmol/l) | 1.95±0.15 | 2.09±0.37 | 2.04±0.24 | 2.07±0.19 | 2.12±0.13 |
| ALP (U/l) | 87.65±32.99 | 202.96±55.16b | 126.67±32.17ad | 136.93±18.60ad | 148.34±29.07bd |
| PICP (µg/l) | 7.59±1.24 | 9.62±1.04a | 7.92±1.81c | 7.76±1.29c | 7.71±0.65c |
| ICTP (µg/l) | 6.20±0.48 | 7.19±0.70b | 6.39±0.78d | 5.67±0.40d | 5.62±0.41d |
Values are expressed as the mean ± standard deviation (n=8).
a
P<0.05 vs. Sham;
b
P<0.01 vs. Sham;
c
P<0.05 vs. OVX;
d
P<0.01 vs. OVX; P-values were calculated using analysis of variance with Student-Newman-Keuls analysis. ASA, aspirin; sCT, salmon calcitonin; OVX, ovariectomized Ca, calcium; Pi, inorganic phosphorus; ALP, alkaline phosphatase; PICP, procollagen type I C-terminal propeptide; ICTP, type I collagen cross-linked telopeptide.