Figure 5.

Methylation analysis of ADAMTS1 in gastric tissue samples. (A) Methylation of ADAMTS1 in primary gastric tumor tissues and corresponding normal gastric tissues. (B) Relative mRNA levels of ADAMTS1 in the unmethylated primary gastric tumor tissues and methylated primary gastric tumor tissues (Mann-Whitney U test; P=0.043). Data are presented as the mean ± standard deviation. N, normal tissue; T, tumor tissue; U, unmethylated; M, methylated; IVD, positive control; H₂O, negative control. ADAMTS1, A disintegrin and metallopeptidase with thrombospondin motif type 1.