Table I.
Methylation of A disintegrin and metallopeptidase with thrombospondin motif type 1 in primary gastric tumor tissues and its association with clinicopathological factors.
| Clinicopathological factor | Number of patients | Methylated (%) | Unmethylated (%) | P-value |
|---|---|---|---|---|
| Gender | 0.435 | |||
| Male | 41 | 19 (46.3) | 22 (53.7) | |
| Female | 15 | 8 (53.3) | 7 (46.7) | |
| Age (years) | 0.540 | |||
| ≥65 | 18 | 9 (50) | 9 (50) | |
| <65 | 38 | 18 (47.4) | 20 (52.6) | |
| Tumor size (cm) | 0.124 | |||
| ≥3 | 34 | 19 (55.9) | 15 (44.1) | |
| <3 | 22 | 8 (36.4) | 14 (63.6) | |
| Differentiation | 0.297 | |||
| Good/moderate | 28 | 12 (42.9) | 16 (57.1) | |
| Poor | 28 | 15 (53.6) | 13 (46.4) | |
| Depth of tumor invasion | 0.048 | |||
| pT1–pT2 | 15 | 4 (26.7) | 11 (73.3) | |
| pT3–pT4 | 41 | 23 (56.1) | 18 (43.9) | |
| TNM stage | 0.015 | |||
| I–II | 17 | 4 (23.5) | 13 (76.5) | |
| III–IV | 39 | 23 (59.0) | 16 (41.0) | |
| Lymph node metastasis | 0.165 | |||
| Positive | 42 | 18 (42.8) | 24 (57.2) | |
| Negative | 14 | 9 (64.3) | 5 (35.7) |
TNM, tumor, node, metastasis.