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. 2015 Jun 4;3:6. doi: 10.1186/s40203-015-0010-5

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© El-Saadi et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Fig. 8 — Predicted aqueous solubility of FC101a and SA. Column graph of predicted aqueous solubility of FC101a hits. All hits display solubility above Simulations-Plus’ proposed high-risk threshold of 0.01 mg/ml (not shown), suggesting the compounds display solubility similar to orally bioavailable drugs. FC101a (shaded in blue) and FC101N exhibit the highest degree of solubility and both fall within the slightly soluble range. Shaded regions indicate solubility based on United States Pharmaceutical (USP) criteria