Table 2.
Approved drugs and corresponding targets used to generate 2D specificity matrix
| No. | Biological target | Corresponding drug |
|---|---|---|
| 1 | Lymphocyte function-associated antigen LFA-1 (CD11A) | Lovastatin |
| 2 | Human Coagulation Factor | 5-dimethyl amino 1-naphthalene sulfonic acid |
| 3 | Retinol-Binding Protein | Fenretinide |
| 4 | Human cardiac troponin C | Bepridil |
| 5 | DNA {d(CGCGAATTCGCG)} | Propamidine (TNT) |
| 6 | Progesterone receptor | Mometasone furoate |
| 7 | Platelet receptor for fibrinogen | Tirofiban |
| 8 | Human phosphodiesterase 4B | Roflumilast |
| 9 | Cyclooxygenase-2 enzyme | Indomethacin |
| 10 | Estrogen receptor | 4-hydroxytamoxifen |
| 11 | ADP/ATP Translocase-1 | Carboxyatractyloside |
Drugs and their corresponding targets are numbered from top to bottom in same order as presented in specificity matrix. Each drug has been FDA approved and is currently on the market