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. 2015 May 2;11:25. doi: 10.1186/s12990-015-0025-2

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© Song et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Spatial analysis of pre-LTP distribution in the ACC. A and B: polygonal diagram of the channels that are activated in the baseline (blue, A) and that undergo pre-LTP (red, B) in 7 slices from 7 mice. Vertical lines denote the layers in the ACC slice. C and D: spatial analysis of the effects of minocycline on pre-LTP distribution maps in the ACC. Shown are the polygonal graphs of activated (blue, C) and pre-LTP-occurring (red, D) channels among the cingulate network when LFS + ATPA is applied in the presence of minocycline (n = 5 slices/5 mice). Spatial distribution of pre-LTP-showing channels is not significantly altered by minocycline.