Fig. 4.

All tested cell lines exhibit large swelling-activated Cl⁻ currents. Response of whole-cell currents to hypotonic bath solution; pipette solution was 0 μM Ca²⁺ with 10 mM EGTA. a Time course of currents in Capan-1 cells as described in “Materials and methods.” Currents at −47 and +93 mV were corrected for liquid junction potential, n = 24 cells. Rate of activation varied among cells. b Currents at +65 mV, measured using the voltage protocol described in legend of Fig. 2. c Steady-state I–V relationships given as mean ± s.e.m. (n) = number of cells