Table 3.
Multivariate analysis exploring the mediators of contrast sensitivity and moderate-to-vigorous physical activity in age-related macular degeneration
| Variable | Interval | Model 0: | Model 1: | Model 2: | Model 3: |
|---|---|---|---|---|---|
| Univariate Modelsa | Multivariate Models | Model 1+ FoF | Model 1+ Driving | ||
| Log CS, binocular | 0.1 Log units worse | 0.86 (0.80, 0.91) | 0.89 (0.83, 0.95) | 1.02 (0.95, 1.10) | 0.93 (0.86, 0.99) |
| FoFb | Person measure score | 1.56 (1.41, 1.73) | -- | 1.70 (1.51, 1.93) | -- |
| Limited driving | vs Driving without limitation | 0.71 (0.45, 1.10) | -- | -- | 0.92 (0.56, 1.52) |
| Not driving | vs Driving without limitation | 0.37 (0.22, 0.61) | -- | -- | 0.40 (0.22, 0.74) |
| Age | 5 y older | 1.07 (0.90, 1.28) | 1.58 (1.28, 1.96) | 1.18 (0.95, 1.46) | 1.69 (1.38, 2.08) |
| Female | vs Male | 0.40 (0.27, 0.59) | 0.33 (0.22, 0.50) | 1.25 (0.81, 1.93) | 0.33 (0.22, 0.49) |
| AA | vs Non-AA | 0.12 (0.02, 0.58) | 0.41 (0.07, 2.46) | 0.30 (0.05, 1.84) | 0.45 (0.08, 2.49) |
| Education | 4 y less | 2.4 (1.6, 3.6) | 2.18 (1.45, 3.26) | 3.94 (2.57, 6.02) | 2.44 (1.61, 3.69) |
| Comorbidity | 1 more Illness | 0.85 (0.87, 0.96) | 0.73 (0.64, 0.83) | 0.81 (0.71, 0.93) | 0.79 (0.70, 0.90) |
MVPA = moderate-to-vigorous physical activity; CS = contrast sensitivity; y = years; FoF = fear of falling; vs = versus; AA = African-American
Values in bold indicate p < 0.05
aMVPA is the dependent variable in each model. Model 0 contains bivariate models of each covariate with MVPA. Model 1 contains CS, Age, Sex, Race, Education, and Comorbidity as independent variables. Model 2 adds FoF as a possible mediator between CS and MVPA
bPerson measure scores are derived from Rasch analytic model. Higher scores indicate greater ability, or less fear of falling