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. 2015 Jun 6;25(2):134–148. doi: 10.1007/s11065-015-9288-7

Table 2.

Summary of results of experimental studies on cognitive procedural learning in Korsakoff’s syndrome

Author Year Sample Task Outcome
Cohen & Squire 1980 4 KS
1 ABD
3 ECT
6 HC
Mirror reading KS, ABD and ECT patients acquired the skill at an equivalent rate as HC and retained it for 3 months.
Martone et al. 1984 8 KS
10 HD
10 HC
Mirror reading KS, but not HD patients acquired the skill at a normal rate, but KS patients did not recognize the words while HD patients did.
Beaunieux et al. 1998 1 KS
1 ALC
10 HC
Mirror reading
Tower of Hanoi
Both cognitive skills were learned at the same rate in KS as in HC and preserved after 1.5 h.
Wood et al. 1982 6 KS Fibonacci’s law All patients showed substantial gain of performance that was somewhat maintained after 1 day and 17 weeks.
Fama et al. 2006 4 KS
9 ALC
6 HC
Gollin Incomplete Picture Test KS, ALC and HC had comparable levels of perceptual learning after correction for visuospatial impairment. Retention was normal after 1 h, but lower after 1 day in the KS patients. There was no transfer of learning over sets of pictures in KS.
Butters et al. 1985 5 KS
1 TUM
1 ENC
15 HD
12 HC
Tower of Hanoi KS, TUM, ENC and HD patients were impaired relative to HC. KS patients showed some evidence of learning.
Beaunieux et al. 2013 14 KS
15 ALC
15 HC
Tower of Toronto 10 KS were able to perform the task, but obtained lower results than both CS and AL.

KS Korsakoff’s syndrome, ALC Alcoholics, HC Healthy Controls, ABD acquired brain damage, HD Huntington’s disease, ECT Electroconvulsive therapy induced amnesia, TUM Brain Tumor, ENC Encephalitic amnesia