Figure 1. Verbal learning plots based on quartiles of white matter hyperintensity and cerebral volume.

Plots are derived from least squares (LS) means in a mixed model after adjusting for age, sex, education, insurance status, race/ethnicity, and presence of subclinical brain infarction. Patients are divided by (A) top quartile of white matter hyperintensity volume (quartile 4) vs the lowest 3 quartiles (quartiles 1–3), and (B) bottom quartile of total cerebral volume (quartile 1) vs the top 3 quartiles (quartiles 2–4). *p < 0.05, **p < 0.01.