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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Reprod Toxicol. 2014 Dec 29;54:110–119. doi: 10.1016/j.reprotox.2014.12.013

FIGURE 1.

FIGURE 1

Outline of generation and treatment of experimental animals. A: F0 generation corresponds to breeders of the studied animals (F1), treated from delivery until weaning of the pups. B: The F1 generation was divided into two groups: nulliparous females treated from PND 1 until PND 181and parous females treated from PND 1 until PND 181, mated at PND 97 and observed during their pregnancy and lactation of their offspring. the F2 generation. For each group, at LD 28 (PND 146), corresponding to the end of lactation for parous rats, three animals per experimental group were sacrificed and mammary glands analyzed. At PND 181 all females were sacrificed and mammary gland examined. Solid triangles (▼) represent conclusion of exposure and sacrifice of animals.