Figure 3. Comparative analysis reveals MeV glycoproteins are exceptionally resistant to insertional mutation.
The total number of sites that could tolerate insertions in each region were normalized to region size and graphed. Red columns indicate the major viral surface glycoproteins. (A) Influenza A virus. The HA1 head domain and HA2 stalk domain of the influenza A virus hemagglutinin are separated in the insert. (B) VEEV (C) HCV. The hyper-variable region of E2 is separated from the rest of the E2 protein in the insert. (D) MeV. All values are out of an arbitrary value of 1.