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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Xenotransplantation. 2015 Apr 3;22(3):211–220. doi: 10.1111/xen.12167

Figure 1. Xenoreactive IgM and IgG binding to GTKO pAECs in baboons receiving Regimens 1, 2, and 3, and modified Regimen 1 (B16311).

Figure 1

No increase in IgM was observed in any of the baboons treated with any of the regimens (A). The baboons treated with Regimen 2 (abatacept-based) developed an elicited anti-pig IgG antibody response (B). An elicited IgG antibody response was not seen in baboons receiving Regimens 1 or 3 or modified Regimen 1 (B).

Relative mean fluorescence intensity (MFI) = MFI of anti-nonGal antibody / MFI of isotype control.