Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In vitro IC50 (µM) of Tumor Cell Line by heterometallic complexes 1 and 3 and reference Ru and Au compounds. All compounds were dissolved in DMSO (1%) before addition to cell culture medium for a 48 h incubation period.
| Compound | L929 | HCT116 | ||||
|---|---|---|---|---|---|---|
| IC50 | IC50 | IC75 | IC90 | |||
| a (Ru) | 243.4±9.9 | 73.7±2.2 | 313.3±7.1 | 1331.4±23.1 | ||
| b (Ru) | 39.6±2.1 | 21.9±1.7 | 228.7±2.3 | 2393.4±24.0 | ||
| c (Au) | 1.7±0.1 | 1.3±0.1 | 1.9±0.2 | 2.7±0.1 | ||
| 1 | 36.1±1.1 | 4.6±0.1 | 9.9±0.2 | 21.5±0.8 | ||
| 3 | 48.6±2.2 | 6.5±0.1 | 12.3±0.2 | 23.2±0.3 | ||
