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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Neurochem. 2015 Apr 23;133(6):857–869. doi: 10.1111/jnc.13103

Figure 1. Rats treated with paclitaxel develop mechanical allodynia and thermal hyperalgesia.

Figure 1

Rats were injected (i.p.) with either vehicle or paclitaxel (2.0 mg/kg) on four alternate days (days 1, 3, 5 and 7). The mean (± SEM) mechanical thresholds of hind paw withdrawal responses (A) and latencies of the withdrawal response to heat stimuli (B) prior to the i.p. injection (Baseline), and on 5 days (5 DPI) and 10 days (10 DPI) post the first injection were plotted. Comparisons of data between baseline and each time point in the paclitaxel group are labeled with *. Comparisons of data between the vehicle group and the paclitaxel group at each time point are indicated with #. Three symbols, P < 0.001.