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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Neurochem. 2015 Apr 23;133(6):857–869. doi: 10.1111/jnc.13103

Figure 4. Tonic GABA receptor activities in the spinal dorsal horn are mainly regulated by GAT-1 under normal conditions.

Figure 4

Data were obtained from normal control rats. (A) Shows recordings of GABAergic currents before and after blocking of GAT-1 with NO-711 (10 μM) and then further inhibition of GAT-3 with SNAP5114 (100 μM). (B) Shows recordings of GABAergic currents before and after blocking of GAT-3 alone with SNAP5114 (100 μM). (C) Shows the mean (± SEM) changes of holding currents induced by NO-711 and then NO-711 plus SNAP5114. ** P < 0.01; *** P < 0.001.