Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Neurochem. 2015 Apr 23;133(6):857–869. doi: 10.1111/jnc.13103

Figure 5. Rats with P-INP have an increased protein expression of GAT-1 and reduced protein expression of GAT-3, which was accompanied with increased GABA uptake activities.

Figure 5

(A) Shows the mean (± SEM) relative density of GAT-1 and GAT-3 to β-Actin in the spinal dorsal horn of rats treated with vehicle and paclitaxel. Samples of GAT-1 and GAT-3 expressions in the spinal dorsal horn at the L4 to L5 segment in paclitaxel and vehicle treated rats are shown. (B) Shows the mean (± SEM) GABA uptake activities obtained from the spinal dorsal horn of rats receiving vehicle and paclitaxel treatment. The GABA uptake activities in the synaptosome preparation from rats treated with paclitaxel treatment were normalized with those treated with vehicle measured at the same time. ** P < 0.01; *** P < 0.001.