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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: J Neurochem. 2015 Apr 23;133(6):857–869. doi: 10.1111/jnc.13103

Figure 7. Mechanical allodynia and thermal hyperalgesia in rats with P-INP are attenuated by an intrathecal injection of a GAT-1 inhibitor.

Figure 7

Line plots show measurements of mechanical thresholds of hind paw withdrawal responses (A) and latencies of the withdrawal response to heat stimuli (B) collected at baseline, 10 days post-i.p. vehicle or paclitaxel injection (10 DPI), and then 30, 60, 180 min and 24 hours after the intrathecal administration of the tested agent. Baseline indicates the measurement before animals received i.p. vehicle or paclitaxel injection. Comparisons between data collected on 10 DPI and at following each time point are indicated with * for the paclitaxel+GAT-1 inhibitor group. Comparisons between the paclitaxel+saline group and paclitaxel+GAT-1 inhibitor group are labeled with #. Two symbols: P < 0.01, three symbols: P < 0.001, data shows mean (± SEM).