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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Biomaterials. 2015 May 19;61:162–177. doi: 10.1016/j.biomaterials.2015.05.028

Table 1.

Highlighting Alginate Polymer Based Nanoparticle Treatments for Assessment of Therapeutic Efficacy

Type of Treatment Description
Blank-Tuftsin Modified Nanoparticles Particle has the macrophage targeting peptide (tuftsin) but does not contain the therapeutic IL-10 encoding plasmid DNA
Unmodified Nanoparticle Particles without peptide on surface but contain therapeutic IL-10 encoding plasmid DNA
Scrambled-Peptide Modified Nanoparticle Particles with scrambled-peptide sequence containing therapeutic IL-10 encoding plasmid DNA
Tuftsin-Peptide Modified Nanoparticle Particles with macrophage targeting-peptide sequence containing therapeutic IL-10 encoding plasmid DNA