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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Clin Immunol. 2015 Apr 8;158(2):148–152. doi: 10.1016/j.clim.2015.03.024

Figure 2.

Figure 2

Comparable mTOR pathway activity in lupus T cells of patients with or without APS. mTORC1 activity was measured by the frequency of cells with elevated intracellular phosphorylated S6 ribosomal protein levels (%pS6RPhi). Left panels show representative histogram overlays, while bar chart depicts the mean ± SEM of fold changes relative to paired controls normalized at 1.0. p values reflect comparison between SLE patients with and without APS using unpaired t-test.