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Y. pestis manganese and zinc transporters functional in vitro. Two widespread Mn transporters (MntH and Yfe/Sit) are functional in Y. pestis. The Znu and Ybt systems are also widespread with the Ybt siderophore and YbtX recently implicated in Zn uptake. Our model shows Zn bound to Ybt. However, this has not been demonstrated and the role of Ybt in Zn acquisition may be indirect.
