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. 2015 Jun 13;15:52. doi: 10.1186/s12894-015-0049-y

Table 4.

Triggers to treatment used in patients under Active Surveillance

Publication Gleason Score on repeat biopsy Positive cores % cancer involvement per single core % positive biopsy cores PSAdt cT (years) PSAv (ng/ml/year) cT
Dall’Era [11] Progression - - - - >0.75 -
Tosoian [18] >6 >2 >50 - - - -
Ercole [13] Progression Increase Increase - - - Upstage
Klotz [14] ≥4 - - - 3 - -
Ischia [15] Progression - - - - - Upstage
Thomsen [16] ≥3 + 4 >3 - - 3 - Upstage
Selvadurai [17] ≥4 + 3 - - >50 - >1 -

cT clinical tumour category, PSAdt prostate-specific antigen doubling time, PSAv PSA velocity