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. Author manuscript; available in PMC: 2016 Jun 9.
Published in final edited form as: Cell Rep. 2015 May 28;11(9):1385–1399. doi: 10.1016/j.celrep.2015.04.062

Figure 4.

Figure 4

Comparative validation of the organ of Corti map. (A-E) For each mouse line expression of GFP and tdTomato is shown in organ of Corti cross-sections. (A′-E′) Bar graphs represent mean gene expression levels per population. (A″-E″) Three in situ maps of the organ of Corti are shown in which individual cells are represented by dots that are color-coded based on marker gene mRNA expression (top), FACS gate origin (middle), and reporter allele mRNA expression (bottom). (F) Confocal images of whole mount preparations of P2 cochleae from Fgfr3-CreERT2/Ai14-tdTomato mice immunolabeled with antibody to hair cell marker myosin 7A. (G) Statistical analyses of mean expression level differences pairwise among all nine cell type groups. Only p-values <0.0001 are shown and indicated by colored lines (red = higher mean expression value, green = lower mean expression value). Scale bars: A-F, 10μm. Related to Figures S6 and S7.