Table 2.
Disease specific treatment by sympathetic of parasympathetic modulation to prevent sudden cardiac death
| Disease | Trigger | Treatment | |
|---|---|---|---|
| Ventircular tachyarrhythmias | |||
| Ischemia & myocardial infarction | Sympathetic | BB, ARB, ACE-I, aspirin, RFCA, ICD, BCSD | |
| Cardiomyopathy | |||
| DCM | Sympathetic | BB, ARB, ACE-I, III, ICD, BCSD | |
| HCM | Sympathetic | BB, Ca-B, III, ICD, BCSD | |
| ARVC | Sympathetic | BB, ARB, ACE-I, III, ICD, BCSD | |
| Arrhythmia | |||
| Long QT syndrome | |||
| LQT1 | Sympathetic | BB, LCSD | |
| LQT2 | Sympathetic | BB, LCSD? | |
| LQT3 | Parasympathetic | Mexiletine, pacemaker, ICD | |
| Brugada Syndrome | Parasympathetic | Quinidine, isoproterenol, ICD BB?, ICD | |
| Idiopathic VF | Sympathetic/Parasympathetic | BB?, ICD Quinidine, isoproterenol, ICD | |
| CPVT | Sympathetic | BB, flecainide, LCSD | |
BB=beta blocker, Ca-B= calcium channel blocker, ACE-I=angiotensin converting enzyme inhibitor, ICD=implantable cardioverter defibrillator, I,II= class I II and III anti arrhythmics, RFCA=radiofrequency catheter ablation, BCSD=bilateral cardiac sympathectomy, LCSD=left cardiac sympathectomy,