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β1-adrenergic receptor expression is down regulated in the right ventricle (RV) of patients with pulmonary arterial hypertension (PAH). (A) A representative cross-sectional image of RV cardiomyocytes and (B) mean values from human tissue microarrays showing down regulation of the β1-adrenergic receptor in hypertrophied RVs from patients with PAH compared to age- and sex-matched controls. Reproduced with permission from reference 16.
