Table 4.
Rates of AAD among patients who received the classes of antibiotics in the ED
| Antibiotic | Number treated (%) | Percentage with AAD (95% CI) |
|---|---|---|
| Cephalosporin | 91 (36.8) | 19.8 (11.4–28.1) |
| Cephalosporin alone | 47 (19.0) | 14.9 (4.3–25.5) |
| Cephalosporin + other | 44 (17.8) | 25.0 (11.7–38.3) |
| Bactrima | 40 (16.2) | 15.0 (3.4–26.6) |
| Vancomycinb | 42 (17.0) | 21.4 (8.5–34.4) |
| Clindamycin | 50 (20.2) | 30.0 (16.8–43.2) |
| Clindamycin alone | 34 (13.8) | 26.5 (10.9–42.1) |
| Clindamycin + other | 16 (6.5) | 37.5 (10.9–64.1) |
| Macrolide | 21 (8.5) | 19.0 (0.7–37.4) |
| Macrolide alone | 13 (5.3) | 7.7 (0.0–24.5) |
| Macrolide + other | 8 (3.2) | 37.5 (0.0–80.7) |
| All penicillinsc | 46 (18.6) | 19.6 (7.7–31.5) |
| Penicillin | 20 (8.1) | 25.0 (4.2–45.8) |
| Penicillin alone | 16 (6.5) | 18.8 (0.0–40.2) |
| Penicillin + other | 4 (1.6) | 50.0 (0.0–100) |
| Penicillin/I | 26 (10.5) | 15.4 (0.5–30.3) |
| Penicillin/I alone | 19 (7.7) | 21.1 (0.8–41.2) |
| Penicillin/I + other | 7 (2.8) | 0.0 |
| Quinolone | 29 (11.7) | 6.9 (0.0–16.7) |
| Quinolone alone | 21 (8.5) | 4.8 (0.0–14.7) |
| Quinolone + other | 8 (3.2) | 12.5 (0.0–42.1) |
| Doxycycline + otherd | 12 (8.5) | 8.3 (0.0–26.7) |
Quinolone = fluoroquinolones, penicillin/I= penicillin inhibitor combination antibiotic.
a
No difference when used as monotherapy or in combination.
b
Used only in combination with other antibiotics.
c
Combining the penicillin and PCN Combo groups.
d
All AAD in combination therapy group; 4 patients in monotherapy did not develop AAD.