Table 1.
Characteristics of patients infected with carbapenem-resistant P. aeruginosa and carbapenem-susceptible P. aeruginosa
| Variable | CRPA (n = 15) | CSPA (n = 65) | p-value |
|---|---|---|---|
| Age-years | |||
| Mean | 47.54 ± 12.7 | 47.45 ± 20.88 | 0.5 |
| Gender–n (%) | |||
| Female | 5(33.34) | 27(41.53) | 0.57 |
| Male | 10(66.66) | 38(58.46) | 0.60 |
| Sexe-ratio | 0.5 | 0.68 | |
| Duration of hospitalization-days | 82.5 ± 45.82 | 63.44 ± 48.82 | 0.04 |
| Ward | |||
| Otorhinolaryngology | 0 | 15(23.07) | 0.06 |
| Endocrinology | 9(60) | 36(53.85) | 0.74 |
| ICU-surgery | 3(20) | 6(9.23) | 0.36 |
| ICU-medecin | 0 | 4(6.15) | 1 |
| Outpatient | 3(20) | 4(6.15) | 0.12 |
| Source | |||
| Diabetic ulcers | 9(60) | 47(70.76) | 0.34 |
| Urine | 4(26.66) | 5(7.7) | 0.08 |
| Blood | 1(6.66) | 0 | 0.18 |
| Aspiration tracheal | 1(6.66) | 13(20) | 0.45 |
| Coexisting diseases | |||
| Trauma | 3(20) | 6(9.23) | 0.36 |
| Diabetes mellitus | 7(46.66) | 35(53.85) | 0.5 |
| Otitis | 0 | 7(10.77) | 0.03 |
| Respiratory disease | 0 | 4(6.15) | 1 |
| Renal disease | 0 | 2(3.07) | 1 |
| Other | 0 | 6(9.23) | 0.5 |
| Previous antibiotics use | 11(73.34) | 59(90.76) | 0.03 |
| Cephalosporin (third-generation) | 10(66.67) | 44(67.69) | 1 |
| Aminoglycoside | 1(6.66) | 12(18.46) | 0.4 |
| Fluroquinolone | 0 | 2(3.07) | 1 |
| Without antibiotic therapy | 4(26.66) | 7(10.77) | 0.2 |
| Invasive devices | 3(20) | 12(18.46) | 1 |
| Urinary catheter | 3(20) | 2(3.07) | 0.04 |
| Intubation | 0 | 5(7.7) | 0.5 |
| Intubation + urinary catheter | 0 | 5(7.7) | 0.5 |
| Polymicrobial infection | 9(60) | 33(50.77) | 0.5 |
| K. pneumoniae | 1(6.66) | 1(1.53) | 0.3 |
| S. aureus | 5(33.34) | 6(9.23) | 0.01 |
| E. coli | 2(13.33) | 8(12.30) | 1 |
| S. aureus + E. coli | 1(6.66) | 4(6.15) | 1 |
| S. aureus + P. mirabilis | 0 | 10(15.38) | 0.19 |
| S. aureus + K. pneumoniae | 0 | 3(4.61) | 1 |
| Mortality | 2(13. 33) | 1(1.53) | 0.09 |
CRPA:carbapenem-resistant P. aeruginosa, CSPA: carbapenem-susceptible P. aeruginosa