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. Author manuscript; available in PMC: 2015 Jun 13.
Published in final edited form as: Cancer. 2010 Jul 15;116(14):3338–3347. doi: 10.1002/cncr.25034

Table 2.

Sites of metastatic disease

At time of Stage IV diagnosis At study entry
Bone 34 (37%) 50 (55%)
Local/regional* 15 (17%) 23 (25%)
Thoracic / Mediastinal 14 (15%) 54 (59%)
Brain 9 (10%) 24 (26%)
Liver 5 (5%) 46 (50%)
Other abdominal/pelvic disease 1 (1%) 14 (15%)
Retroperitoneum – 12 (13%)
Cerebrospinal fluid – 8 (8%)
Other 1 (1%) 7 (7%)
Unknown 1 (1%) –
1 site of metastatic disease
>1 site of metastatic disease		 80 (88%)
11 (12%)		 7 (8%)
84 (92%)
*

8 patients with supraclavicular lymph node disease were classified as stage IV prior to 2002 as dictated by the 5th edition of the AJCC Cancer Staging Manual. The remaining local/regional sites at time of stage IV diagnosis included: brachial plexus disease, cervical node involvement, and contralateral intramammary node disease.